He attended Oklahoma State, where he earned All-Big 12 Conference honors on their baseball team. In the summer of Template:By, he played for the Falmouth Commodores of the Cape Cod Baseball League. He also played baseball at Indian River Community College. Luke spent a winter playing for a Venezuelan League where he earned the nickname "el monstruo de cuadrangular" which translates to "The Home Run Monster". He spent his first professional season in Template:By at home recovering from Tommy John surgery on his elbow joint.
Scott became the first Astros' rookie to hit for the cycle, accomplishing a "reverse natural cycle" (home run, triple, double, and single, in that order) on July 28, Template:Mlby. That feat also marked Scott's first career home run. After the completion of the Template:MLBy season Scott headed to Venezuela to play another season in the Winter League.
On July 7, 2009, Scott had a career high seven RBIs against the Seattle Mariners, going 3-4 with a single, triple, and home run.
Scott was named Most Valuable Oriole for the 2010 season.
<ref>tags exist, but no
<references/>tag was found